Archives of Clinical and Biomedical Research

ISSN

2572-5017

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Abstract

The Use of Allogeneic Leukocytes Infusion in Cancer Immunotherapy

Mixed allogeneic lymphocyte response has activated considering T lymphocytes and elicit type 1 cytokines which induced antitumor immunity. Using TC-1 cancer model, we demonstrated the response of inactivated allogeneic leukocytes infusion (ALI) to generate antitumor immune response. In TC-1 tumor model, ALI induced a delayed cancer development and a prolonged survival. Our study illustrated that ALI might elicit strong antitumor immune response. The method strategy would be easy and efficient strategy in tumor immunotherapy.

Author(s):

Yishu Tang, Chunxia Zhou, Wenbo Ma, Dongmei Wang, Shuren Zhang

Abstract PDF Full Text View at Academia.edu
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